Diabetes Compounding
“Psychological stress decreases insulin sensitivity and increases insulin resistance and may hence be important in the development/onset of type I diabetes.”
Neuroimmunomodulation. 2006;13(5-6):301-8. Epub 2007 Aug 6.
Psychological stress and the risk of diabetes-related autoimmunity: a review article.
Sepa A, Ludvigsson J.
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“In patients with glucose intolerance, cortisol secretion, although normal, is inappropriately high given enhanced central and peripheral sensitivity to glucocorticoids……thus altered cortisol action occurs not only in obesity and hypertension but also in glucose intolerance and could therefore contribute to the link between these multiple cardiovascular risk factors.”
J Clin Endocrinol Metab. 2002 Dec;87(12):5587-93.
Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance.
Andrews RC et al.
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