The Miracle Molecule

Nitric Oxide

Nitric oxide is a signaling molecule and a gas. It tells the arteries to relax, which improves circulation and blood flow. The discovery of this “miracle molecule” won the Nobel Prize in 1998 and was named “Molecule of the Year” in 1992.

Nitric oxide carries messages at the cellular level, able to efficiently penetrate cellular membranes because of its gaseous structure. N-O is abundant in the body, but it is unstable and short-lived, and thus must be renewed continuously

It has been found that nitric oxide improves support for circulation and blood flow and has been linked to a variety of health benefits, including helping:

  • Support cardiovascular and heart health
  • Support healthy blood pressure levels
  • Promote artery dilation for healthy blood flow
  • Promote increased circulation throughout the body
  • Support healthy arterial function
  • Support normal, healthy circulation


Nitric Oxide Deficiency

The good news is that our bodies produce an abundance of nitric oxide. The not-so-good news is that nitric oxide molecules have a very short lifespan and must be renewed constantly. In our teens and 20s, this isn’t a problem. As we age, however, our bodies begin to produce less nitric oxide.

In fact, by age 40:

  • Men produce about 50% of the nitric oxide they did in their 20
  • Women produce about 35%  of the nitric oxide they did in their 20s

In addition to aging, other factors can play a role in nitric oxide deficiency. The use of mouthwash, for example, can kill off healthy bacteria that help promote nitric oxide production. Prescription and medications taken for heartburn or acid reflux can also contribute to nitric oxide deficiency.

Restoring Nitric Oxide Levels

Clinical strength nitric oxide restoration formula, with added methylfolate (folic acid supplement) for increased efficacy 

Patented, quick-dissolve tab clinically proven to generate nitric oxide in the mouth. The biphasic mechanism of action provides an immediate, rescue source of NO as well as a reserve pool of nitrate and nitrite, which the body can convert to NO in the endothelium (the tissue that forms a single layer of cells lining various organs and cavities of the body, especially the blood vessels, heart, and lymphatic vessels. as needed) Optimal NO levels may help:

  • Promote artery dilation for healthy blood flow
  • Promote increased circulation throughout the body
  • Support healthy blood pressure levels
  • Support cardiovascular and heart health
  • Support healthy arterial function

N-O Production Loss: The Missing Link in Age-Related Health Problems

The medical literature has clearly established the significance of nitric oxide (NO) homeostasis in human physiology. Essentially, NO acts as an endogenous regulator of the intracellular availability of oxygen and is critical for normal mitochondrial function (production of energy.

Continuous generation of NO is essential for cardiovascular integrity. This level of correlation, however, is often not reflected in the treatment or management of patients, as evidenced by the fact that no effective therapeutic drug has been developed to reestablish NO homeostasis.

However, after years of research and development at the University of Texas, Dr. Nathan Bryan and his team were able to formulate a tab that  activates in saliva to induce the rapid production of NO gas to restore NO homeostasis*. The Neo40 technology is biphasic in nature. The first phase delivers authentic NO gas as the tab is dissolving. The second phase provides the substrates and cofactors necessary for restoring constitutive NO production in the blood vessels.


Though originally intended as a pharmaceutical, Neo40 is a nutraceutical (a food containing health-giving additives and having medicinal benefit)  that is considerably less costly than its drug model. Neo40 is the only NO technology that is scientifically validated, clinically tested, and patent protected.

* Homeostasis is a key concept in understanding how our body works. It means keeping things constant and comes from two Greek words: 'homeo,' meaning 'similar,' and 'stasis,' meaning 'stable.' A more formal definition of homeostasis is a characteristic of a system that regulates its internal environment and tends to maintain a stable, relatively constant condition of properties. 

Homeostasis is happening constantly in our bodies. We eat, sweat, drink, dance, eat some more, have salty fries, and yet our body composition remains almost the same. If someone were to draw your blood on ten different days of a month, the level of glucose, sodium, red blood cells and other blood components would be pretty much constant, regardless of your behavior (assuming fasting before drawing blood, of course). 


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